The image for Bristol that they use on their website is one of boats in the floating harbour instead of the usual suspension bridge one -- I like them already!
Not entirely sure who this route is for exactly, but I suspect it's not really for connecting passengers.
Tue/Thu is as good as it gets I suppose for twice-weekly.
FRA airport is really well connected by train, so this provides easy access to a region which must have about 10-15 million people within easy reach.
Also looks like they will be operating A320s, so a few more seats to fill than with the Embraers.